5-HTP

5-HTP is the precursor to serotonin, a neurotransmitter involved in regulating many body processes like mood, sleep, and appetite. 5-HTP can increase levels of serotonin in the brain, which may reduce symptoms of depression and reduce appetite.

• mood support (via serotonin increase)
• improved sleep quality (melatonin precursor)
• reduced appetite and potential weight loss
• migraine reduction

Popular Manufacturers

Contraindications

• pregnancy and lactation — consult clinician
• major surgery — discontinue at least 2 weeks prior
• use with serotonergic drugs — contraindicated

Potential Side Effects

• gastrointestinal upset (nausea, vomiting, diarrhea)
• anxiety, shivering
• heart palpitations, irregular heartbeat
• drowsiness or vivid dreams
• rare: eosinophilia-myalgia syndrome (possibly contaminant-related)
• risk of serotonin syndrome at high doses or with interactions